Investigation on the mechanism of transmembrane transport of mycophenolate mofetil and its active metabolite mycophenolic acid

• In: Posters
• At: Dublin (Ireland) (2013)
• Type: Poster
• By: YU, Zicheng (Shanghai Yangpu District Central Hospital, Department of Pharmacy, Shanghai, China)
• Co-author(s): Tian, Wei W (Shanghai Yangpu District Central Hospital, Shanghai, China)
  Ma, Ming H. (Shanghai Yangpu District Central Hospital, Shanghai, China)
  Liu, Xia (Shanghai Yangpu District Central Hospital, Shanghai, China)
  Chen, H.J. (Shanghai Yangpu District Central Hospital, Shanghai, China)
  Chen, H.Z. (Shanghai Jiao Tong University School of Medicine, Shanghai, China)
  
• Abstract:

  
  Background:
  Mycophenolate mofetil (MMF) is an important immunosuppressive drugs. After oral administration, MMF and its active metabolite MPA pharmacokinetics shows great variability in individual patients, leading to different immunosuppressive effect.
  
  
  Aims:
  To investigate the mechanism of transmembrane transport of mycophenolate mofetil (MMF)
  
  ..

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