The design of novel lead molecules using a bioisosteric approach

• In: Posters
• At: Dublin (Ireland) (2013)
• Type: Poster
• By: AZZOPARDI, Lilian (University of Malta, Msida, Malta)
• Co-author(s): Schembri, Maria (University of Malta, Msida, Malta)
  Shoemake, Claire (University of Malta, Msida, Malta)
  
• Abstract:

  
  Background:
  The identification of lead molecules which can be developed into drugs with clinical utility is a challenge in contemporary rational drug design. Bioisosteric manipulation and de novo design are often resorted to in this respect. This project implemented bioisosteric modification on a selected small molecule cohort in the context of a
  ..

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