Pulsatile release of bambuterol using novel ph-sensitive polymeric systems

• In: Industrial Pharmacy Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: IPS-P-032
• By: LEE, Beom-Jin (Kangwon National University, Chuncheon, South-Korea)
• Co-author(s): Tran, Phuong (Kangwon National University, CHUNCHEON, South-Korea)
  Tran, Thao (Kangwon National University, CHUNCHEON, South-Korea)
  Park, Young Min (Kangwon National University, CHUNCHEON, South-Korea)
  Choe, Jae Seung (Eura Pharm. Inc.,, SUWON, South-Korea)
  Kim, Ji Tae (Eura Pharm. Inc.,, SUWON, South-Korea)
  Kim, Young Choong (Seoul National University, SEOUL, South-Korea)
  Chung, Kyu Hyuck (Sungkyunkwan University, SUWON, South-Korea)
  
• Abstract:

  The aims of this work were to design pH-sensitive pulsatile drug delivery system which exposes an "on/off"pulse release of drug. Bambuterol to treat asthma was selected as a model drug. Binary blends of polyacrylic acid (PAA) and ethyl cellulose (EC) with different ratios were used for coatings as pH sensitive polymeric systems. PAA, a

  ..

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