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Population pharmacokinetics of 3-ap
- In: Hospital Pharmacy Posters
- At: Lisbon (Portugal) (2010)
- Type: Poster
- Poster code: HPS-P-036
- By: KOLESAR, Jill (University of Wisconsin, Madison, United States of America)
- Abstract:
Purpose:The purpose of this study was to develop a population pharmacokinetic (PK) model for 3-AP pharmacokinetics and to evaluate the effect of ABCB1 polymorphisms on the pharmacokinetic profile of 3-AP and to assess the relationship between 3AP disposition and patient covariates. Methods: A total of 40 patients with advanced cancer from two..
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