Population pharmacokinetics of 3-ap

• In: Hospital Pharmacy Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: HPS-P-036
• By: KOLESAR, Jill (University of Wisconsin, Madison, United States of America)
• Abstract:

  Purpose:The purpose of this study was to develop a population pharmacokinetic (PK) model for 3-AP pharmacokinetics and to evaluate the effect of ABCB1 polymorphisms on the pharmacokinetic profile of 3-AP and to assess the relationship between 3AP disposition and patient covariates. Methods: A total of 40 patients with advanced cancer from two..

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