Preparation of silymarin-loaded solid dispersion with enhanced solubility using pvp k30, tween 80 and water

• In: Industrial Pharmacy Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: IPS-P-011
• By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
• Co-author(s): Yang, Kwanyeol (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Yeo, Woohyun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Yi, Jeong-Hun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Cho, Jung Hyun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  Seo, Youngee (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  
• Abstract:

  To design a novel silymarin-loaded solid dispersion with enhanced solubility, various silymarin-loaded solid dispersions were prepared with water, polyvinylpyrrolidone (PVP) K30 and Tween 80, employing surface-attached method. The optimized carrier was selected by solubility and dissolution tests. The effects of PVP K30 and Tween 80 on the aqueous ..

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