Development and optimization of multiple-unit controlled release dosage form of a highly water soluble for once-daily administration

• In: Industrial Pharmacy Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: IPS-P-010
• By: BASALIOUS, Emad (Faculty of pharmacy, Cairo university, Cairo, Egypt)
• Co-author(s): Shoukri, Raguia (Faculty of pharmacy, Cairo university, CAIRO, Egypt)
  Shamma, Rehab (Faculty of pharmacy, Cairo university, CAIRO, Egypt)
  
• Abstract:

  A controlled release multiple-unit preparation of betahistine diHCl (BHCL), a short half-life freely water soluble drug, was developed to allow once-daily administration to improve patient compliance. BHCL was complexed with cation exchange resins having different particle size and degree of cross linking. BHCL-resin complex that provided the..

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