Relationships between thiopurine s-methytransferase polymorphism and azathioprine-related adverse drug reactions in Chinese renal transplant recipients

• In: SIG: Pharmaceutical Biotechnology - Posters
• At: Basel (Switzerland) (2008)
• Type: Poster
• Poster code: PB-P-010
• By: XIN, Huawen (Wuhan General Hospital of Guangzhou Command, Wuhan, China)
• Co-author(s): Xiong, Hui (Wuhan General Hospital of Guangzhou Command, WUHAN, China)
  
• Abstract:

  Aim--Azathioprine (AZA) is a thiopurine prodrug commonly used in triple-immunosuppressive therapy in renal transplant recipients. However, its use has been complicated by a high incidence of serious adverse drug reactions such as hematotoxicity and hepatotoxicity. The aim for this study is to systematically investigate the relationships between

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