First-generation antihistamine-induced drowsiness and the CYP2D6 genotype

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-E-023-Monday
• By: MIURA, Jun (Hokkaido Pharmaceutical University, Pharmacotherapy, Sapporo, Japan)
• Co-author(s): Jun Miura: Pharmacotherapy, Hokkaido Pharmaceutical University, Sapporo, Japan
  Hiromi Motomura: Pharmacotherapy, Hokkaido Pharmaceutical University, Sapporo, Japan
  Taito Ishizaki: Pharmacotherapy, Hokkaido Pharmaceutical University, Sapporo, Japan
  Kaori Yama: Pharmacotherapy, Hokkaido Pharmaceutical University, Sapporo, Japan
  Shigenori Tadokoro: Health Administration Center, Muroran Institute of Technology, Muroran, Japan
  Haruki Sasaki: Health Administration Center, Muroran Institute of Technology, Muroran, Japan
  Maiko Machida: Pharmacotherapy, Hokkaido Pharmaceutical University, Sapporo, Japan
  Nobumasa Hayase: Pharmacotherapy, Hokkaido Pharmaceutical University, Sapporo, Japan
  
• Abstract:

  Backgrounds

  Marked inter-individual variation in the activity of cytochrome P450 (CYP) 2D6 has been reported. The variation is, at least in part, due to the genetic polymorphisms. Therefore, genotyping of CYP2D6 might be useful in expecting individual responses to the substrate drugs. 

  Aims

  This study aims to investigate the relation between the CYP2D
  ..

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