Physicochemical and dissolution properties of ibuprofen-DEAE-Dextran nanoconjugates prepared by hydrotropic solubilization

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-112-Tuesday
• By: KOLA-MUSTAPHA, Adeola (University of Ilorin, Ilorin Nigeria, Ifako-Ijaye, Nigeria)
• Co-author(s): Adeola Tawakalitu Kola-Mustapha: Pharmaceutics and Industrial Pharmacy, University of Ilorin, Ilorin, Nigeria
  Amos Olusegun Abioye: School of Pharmacy, De Montfort University, Leicester, United Kingdom
  
• Abstract:

  Backgrounds

  Ibuprofen, a BCS class II drug requires a high loading dose to be effective. In this study, the possibility of combining polyelectrolytes with hydrotropes was explored to form secondary complexes with effects on release profiles and stability of novel nanoconjugates.  

  Aims

  To enhance the solubility of ibuprofen by the combined advantage

  ..

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