Effect of surfactants in a resveratrol amorphous solid dispersion

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-041-Monday
• By: VASCONCELOS, Teofilo (BIAL, R & D department, Trofa, Portugal)
• Co-author(s): Teofilo Vasconcelos: R & D department, BIAL, Trofa, Portugal;I3S, Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal;Biocarrier Group, Instituto de Engenharia Biomédica, University of Porto, Porto, Portugal;ICBAS-UP, Instituto de Ciências Biomédicas Abel Salazar - Universidade do Porto, Porto, Portugal
  Sara Marques: CIBIO/InBIO-UP, Research Centre in Biodiversity & Genetic Resources, University of Porto, Porto, Portugal;ICBAS-UP, Instituto de Ciências Biomédicas Abel Salazar - Universidade do Porto, Porto, Portugal
  Bruno Sarmento: Biocarrier Group, Instituto de Engenharia Biomédica, University of Porto, Porto, Portugal;I3S, Instituto de Investigação e Inovação em Saúde, University of Porto, Porto, Portugal;CESPU, Instituto de Investigação e Formação Avançada em Ciências e Tecnologias da Saúde & Instituto Universitário de Ciências da Saúde, Gandra, Portugal
  
• Abstract:

  Backgrounds

  Resveratrol (RES) is a poor water soluble drug with deprived intrinsic oral permeability, also due to high premature metabolization and to intestinal efflux. Thus, the formulation of resveratrol in a final solid dispersion (SD) may improve the solubility in the gastrointestinal tract. 

  Aims

  Evaluate the impact of further inclusion of
  ..

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