Evaluating Drug Supersaturation Propensity: Comparison of Different Methods

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-032-Monday
• By: MULLERTZ, Anette (University of Copenhagen, Pharmacy, Copenhagen Ø, Denmark)
• Co-author(s): Christoffer Hansen: Pharmacy, University of Copenhagen, Copenhagen, Denmark
  Jakob plum: Pharmacy, University of Copenhagen, Copenhagen, Denmark
  Thomas Rades: Pharmacy, University of Copenhagen, Copenhagen , Denmark
  Anette Müllertz: Pharmacy, University of Copenhagen, Copenhagen, Denmark
  
• Abstract:

  Backgrounds

  Evaluation of drug supersaturation propensity helps selecting a delivery strategy for poorly soluble drugs. Supersaturation can be induced by different methods, e.g. solvent shift, pH shift and dissolution of amorphous solids; however, similarities between these methods have not yet been assessed.

  Aims

  To compare supersaturation of four

  ..

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