You can access any of the podium or poster presentations’ abstracts by searching for it below. For the 2026 FIP world congress in Montreal, presentations and summaries from invited speakers are available below, while abstracts are published in the Pharmacy Education Journal (PEJ) here.
Export this Abstract | Print this Abstract |
Add to my preferred Abstracts list |
My preferred Abstracts list (5) |
Back to Search
Physiologically-based approach to predict dopamine D2 receptor occupancy of antipsychotics in brain: translation from rat to human
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-092-Tuesday
- By: WONG, Yin Cheong (Leiden University, Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden, Netherlands)
- Co-author(s): Yin Cheong Wong: Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden Univeristy, Leiden, Netherlands
Maddalena Centanni: Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden Univeristy, Leiden, Netherlands
Elizabeth de Lange: Division of Pharmacology, Leiden Academic Centre for Drug Research, Leiden University, Leiden, Netherlands - Abstract:
Backgrounds
Receptor occupancy (RO) is a translational biomarker for assessing drug efficacy, which could facilitate both dose optimization of existing drugs and evaluation of drug candidates.
Aims
We aimed to apply a physiologically-based pharmacokinetic (PBPK) modeling approach to predict the dopamine D2 RO of antipsychotics.
Methods
Risperidone
.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
Please login
Last update 23 September 2026