Studies on the Electrophysiological Mechanism of IMM-302 to Improve Learning and Memory in animal model

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-051-Tuesday
• By: GUO, Tingting (Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Pharmacology, Beijing, China)
• Co-author(s): Tingting Guo: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  Xiaomei Jiang: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  Weiping Wang: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  Xiaoliang Wang: Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
  
• Abstract:

  Backgrounds

   IMM-302 exhibited the therapeutic effects on cognitive deficits in the preclinical studies. However, the mechanisms of IMM-302 are still unknown.

  Aims

  In this study, we investigated the effects of IMM-302 on ion channels related to GABA_A, NMDA and AMPA receptors. 

  Methods

  1) Morris water maze test was used to evaluate the behavior of
  ..

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