EPIGENETIC THERAPY AUGMENTS DOCETAXEL IN THE TREATMENT OF BREAST CANCER: AN IN VITRO AND IN VIVO EVALUATION

• In: Poster Session
• At: Düsseldorf (Germany) (2015)
• Type: Poster
• By: JAIN, Prateek (MCOPS, Manipal University, Manipal, India)
• Co-author(s): Prateek Jain
  
• Abstract:

  Docetaxel (DTX) is one of the most effective chemotherapeutic agents in the treatment of breast cancer. Unfortunately, there is altered response to DTX due to resistance. DNA methylation, an epigenetic event, plays a vital role in cancer and chemotherapy drug resistance. Exploiting the gene reactivation by using epigenetically acting agents in

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