EFFECTS OF GASTROINTESTINAL SURGERY ON ORAL DRUG ABSORPTION

• In: B2 - Reducing inter-individual variability: the power of a practitioner/scientist team approach on Thursday, 1 October 2015, 14:30-17:30
• At: Düsseldorf (Germany) (2015)
• Type: Presentation
• By: JOHNSON, Trevor (Simcyp Limited (a Certara company), Research and Development, Sheffield, United Kingdom)
• Co-author(s): Trevor N Johnson
  
• Abstract:

  Bariatric surgery has proved to be successful in treating morbid obesity via procedures such as sleeve gastrectomy, Roux-en-Y gastric bypass and the more invasive bilio-pancreatic diversion with duodenal switch. 

   

  Such interventions are known to affect the bioavailability of orally administered drugs through modification of various

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