Development of a methodology to measure the effect of divalent cations on the transport of calcium by the plasma membrane calcium pump.

• In: SIG Pharmaceutical Biotechnology - Poster Session
• At: Salvadore (Brazil) (2006)
• Type: Poster
• Poster code: PB-P-004
• By: MARTIARENA, Jorge Luis (Faculty of Pharmacy and Biochemistry, Buenos Aires, Argentina)
• Co-author(s): Rossi, Juan Pablo (IQUIFIB, BUENOS AIRES, Argentina)
  
• Abstract:

  The plasma membrane calcium pump (PMCA) is a fundamental mechanism to remove Ca2+ from the cytoplasm of all eukaryotic cells. PMCAs, like all members of the superfamily of P-type ATPases catalyze the hydrolysis of ATP. There are four genes encoding mammalian PMCAs. The diversity of PMCAs is further increased by alternative RNA splicing that..

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