Synthesis and evaluation of novel thiobarbiturates as anticancer agents

• In: Posters
• At: Dublin (Ireland) (2013)
• Type: Poster
• By: FARRAG, Amel (Faculty of Pharmacy, Al-Azhar university, Pharmaceutical chemistry, Hellopolis, Cairo, Egypt)
• Co-author(s): Elzahabi, Heba (Faculty of Pharmacy, Al-Azhar university, Cairo, Egypt)
  Khalifa, Maha (Faculty of Pharmacy, Al-Azhar university, Cairo, Egypt)
  Gado, Yomna (Faculty of Pharmacy, Al-Azhar university, Cairo, Egypt)
  
• Abstract:

  Thiobarbiturates attract great attention in medicinal chemistry field as It explored a broad range of biological activity [1]. Also, 2-thiobarbituric acids have been reported as promising anticancer agents [1]. Herein, some novel thiobarbiturate derivatives were afforded and screened as antiMCF-7 cancer cell line. Synthetic pathway started with

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