Variation of Valproic Acid Concentration During Concomitant Use of Carbapenem Antibiotics and Enzyme-Inducing Antiepileptic Drugs: A Retrospective Study

• In: Posters
• At: Amsterdam (the Netherlands) (2012)
• Type: Poster
• Poster code: HPS-P-143
• By: TANG, Lian (Suzhou Municipal Hospital, Department of Pharmacy Department, Suzhou, China)
• Co-author(s): Zhuang, W. (Suzhou Municipal Hospital, Suzhou, China)
  Yu, X. (Suzhou Municipal Hospital, Suzhou, China)
  Yang, C. (Suzhou Municipal Hospital, Suzhou, China)
  Shang, E.N. (Suzhou Municipal Hospital, Suzhou, China)
  
• Abstract:

  
  Background:
  Several studies have described a remarkable interaction between carbapenems and valproic acid (VPA). However, there’s no data evaluating the influence of enzyme-inducing antiepileptic drugs (AEDs) on VPA level co-administered with carbapenems.
  Aims:
  To analyze the variation of VPA level following administered concomitantly of VPA,

  ..

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