EVALUATION AND FORMULATION OF LIQUISOLID COMPACTS OF KETOCONAZOLE USING CENTRAL COMPOSITE DESIGN

• At: AbuDhabi (United Arab Emirates) (2019)
• Type: Poster
• Poster code: POS-FDP-016
• By: LUITEL, Anup (Kathmandu University, Department of Pharmacy, Nepal)
• Co-author(s): Anup Luitel: Department of Pharmacy, Kathmandu University, Dhulikhel-4, Kavreplanchok, Nepal
  Uttam Budathoki: Department of Pharmacy, Kathmandu University, Dhulikhel-4, Kavreplanchok, Nepal
  Panna Thapa: Department of Pharmacy, Kathmandu University, Dhulikhel-4, Kavreplanchok, Nepal
  
• Abstract:

  Background

  Ketoconazole is a broad-spectrum anti-fungal imidazole derivative, class II of BCS and exhibits poor aqueous solubility and high permeability is a 2nd generation drug indicated for different forms of candidoses.

  Methods

  Liquisolid compact was prepared using PEG 400(liquid vehicle), MCC PH 102(carrier material) and Aerosil 200(coating
  ..

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