Evidence-based pharmacogenetic guidelines in the Netherlands

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-E-009-Tuesday
• By: CHEUNG, Ka-Chun (Royal Dutch Pharmacists Association, Medicine Information Centre, DEN HAAG, Netherlands)
• Co-author(s): Ka-Chun Cheung: Health research and innovation, Royal Dutch Pharmacists Association, DEN HAAG, Netherlands
  Marga Nijenhuis: Medicines Information Centre, Royal Dutch Pharmacists Association, DEN HAAG, Netherlands
  Mandy Crommentuijn – van Rhenen: Medicines Information Centre, Royal Dutch Pharmacists Association, DEN HAAG, Netherlands
  Inge Holsappel: Medicines Information Centre, Royal Dutch Pharmacists Association, DEN HAAG, Netherlands
  
• Abstract:

  Backgrounds

  In recent years a number of scientific studies have shown that genetic variation in genes encoding drug transporters and drug metabolic enzymes affects drug disposition leading to under-dosing or overdosing in affected individuals. Drug response is a complex trait with significant interindividual variability. Therefore, application of..

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