Formulation of a taste masked fixed dose combination of rifampicin and isoniazid by hot melt extrusion

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-C-039-Monday
• By: KEATING, Alison (UCL School of Pharmacy, Pharmaceutics, London, United Kingdom)
• Co-author(s): Alison Keating: UCL School of Pharmacy, London, United Kingdom
  Catherine Tuleu : UCL School of Pharmacy, London, United Kingdom
  Claire Forbes: Pfizer UK Ltd, Sandwich , United Kingdom
  Min Zhao: Queens University Belfast , Belfast , United Kingdom
  Duncan Craig: UCL School of Pharmacy, London, United Kingdom
  
• Abstract:

  Backgrounds

  Non-adherence to anti-tuberculosis (TB) treatment is a major cause of treatment failure and of the emergence of drug-resistant TB. Fixed dose combinations (FDCs) have been suggested to improve adherence which is quite low, particularly in paediatric patients. By using an FDC the tablet burden on the patient is reduced, dose calculations ..

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