Distribution of model macromolecule drug in whole brain, nasal mucosa, and trigeminal nerve in rats after intranasal administration with basic peptide based nanocarriers

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-093-Tuesday
• By: KANAZAWA, Takanori (Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan)
• Co-author(s): Takanori Kanazawa: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  Mami Kaneko: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  Takaki Niide: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  Hisako Ibaraki: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  Yuuki Takashima: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  Yasuo Seta: School of Pharmacy, Tokyo University of Parmacy and Life Sciences, Tokyo, Japan
  
• Abstract:

  Backgrounds

  Nose-to-brain delivery is a highly versatile route, which, in combination with novel drugs, is a promising approach  for intractable CNS disorders. Furthermore, nano-sized drug carriers may improve nose-to-brain drug delivery.

  Aims

  To investigate the nose-to-brain pathway using nanocarriers, the time-dependent distribution of model

  ..

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