Biological activity of isoniazid chitosan microparticles in alveolar macrophages

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-037-Tuesday
• By: OLIVEIRA, Paula (University of Brasília, Faculty of Health Sciences, Brasília, Brazil)
• Co-author(s): Paula Oliveira: LTMAC, University of Brasília, Brasília, Brazil
  Priscilla Pereira: FCFRP, Universidade de São Paulo, Ribeirão Preto, Brazil
  Breno Noronha: LTMAC, University of Brasília, Brasília, Brazil
  Tais Gratieri: LTMAC, University of Brasília, Brasília, Brazil
  Lucia Faccioli: FCFRP, Universidade de São Paulo, Ribeirão Preto, Brazil
  Marcílio Cunha-Filho: LTMAC, University of Brasília, Brasília, Brazil
  Guilherme Gelfuso: LTMAC, University of Brasília, Brasília, Brazil
  
• Abstract:

  Backgrounds

  Tuberculosis current treatment is systemic and required high doses of drugs that cause several adverse effects.

  Aims

  This study aimed to obtain and characterize isoniazid (INH) loaded chitosan microparticles (MPs) to pulmonary route and to evaluate in vitro their biological activities in alveolar macrophages.

  Methods

  MPs were prepared with
  ..

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