The use of Caco-2 cells to evaluate drug absorption from lipid-based formulations

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-026-Tuesday
• By: KEEMINK, Janneke (Uppsala University, Department of Pharmacy, Uppsala, Sweden)
• Co-author(s): Janneke Keemink: Department of Pharmacy, Uppsala University, Uppsala, Sweden
  Christel A.s Bergström: Department of Pharmacy, Uppsala University, Uppsala, Sweden
  
• Abstract:

  Backgrounds

  An increasing number of drug candidates exhibit low solubility. Lipid-based formulations (LBFs) are used to enhance solubility of these compounds in the GI tract. Typically in vitro digestion is used to evaluate the LBF performance prior to in vivo studies.

  Aims

  To evaluate the conditions that allow the use of Caco-2 monolayers in the

  ..

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