In vitro CACO-2 cell permeability studies of ritonavir nanosuspension formulation

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-005-Tuesday
• By: CELEBI, Nevin (Gazi University Faculty of Pharmacy, Pharmaceutical Technology, Ankara, Turkey)
• Co-author(s): Alptug Karakucuk: Pharmaceutical Technology, Gazi University Faculty of Pharmacy, Ankara, Turkey
  Naile Ozturk: Pharmaceutical Technology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
  Imran Vural: Pharmaceutical Technology, Hacettepe University Faculty of Pharmacy, Ankara, Turkey
  Zeynep Safak Teksin: Pharmaceutical Technology, Gazi University Faculty of Pharmacy, Ankara, Turkey
  Nevin Celebi: Pharmaceutical Technology, Gazi University Faculty of Pharmacy, Ankara, Turkey
  
• Abstract:

  Backgrounds

  Nanosupensions provide benefits to improve saturation solubility, dissolution and permeability of drugs related to their nanosized particles.

  Aims

  The objective of this study was to evaluate cytotoxic effect and permeability of ritonavir nanosuspension on Caco-2 cells in comparison with coarse ritonavir powder and physical mixtures. 

  Method

  ..

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