Molecular Dynamics simulations of colloidal structures in aspirated human intestinal fluids

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-036-Monday
• By: PARROW, Albin (Uppsala University, Department of Pharmacy, Uppsala, Sweden)
• Co-author(s): Albin Parrow: Department of Pharmacy, Uppsala University, Uppsala, Sweden
  Christel A. S. Bergström: Department of Pharmacy, Uppsala University, Uppsala, Sweden
  Per Larsson: Department of Pharmacy, Uppsala University, Uppsala, Sweden
  
• Abstract:

  Backgrounds

  To more accurately predict intestinal drug solubility the colloidal structures in the intestinal fluid is of importance. In the fasted state these are composed mainly of bile salts and phospholipids that may solubilize hydrophobic compounds significantly. One potential approach to explore these colloidal structures is by molecular

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