Preparation and evaluation of doxorubicin-loaded human serum albumin nanoparticles

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-B-026-Monday
• By: KIMURA, Kotaro (Kumamoto, Japan)
• Co-author(s): Kotaro Kimura: Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan
  Keishi Yamasaki: Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan;DDS Resarch Institute, Sojo University, Kumamoto, Japan
  Kazuaki Taguchi: Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan
  Hideaki Nakamura: Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan
  Mamoru Haratake: Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan
  Masaki Otagiri: Faculty of Pharmaceutical Sciences, Sojo University, Kumamoto, Japan;DDS Resarch Institute, Sojo University, Kumamoto, Japan
  
• Abstract:

  Backgrounds

  Human serum albumin (HSA) has been shown to be biocompatible and bind vriety of drugs. Therefore, it is ideal as a carrier of a drug in cancer therapy. In cancer treatment using carriers, it is known that nanoparticles showing a size of 60 to 130 nm exhibit high tumor accumulation due to the EPR (enhanced permeability and retention)..

The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login