You can access any of the podium or poster presentations’ abstracts by searching for it below. For the 2026 FIP world congress in Montreal, presentations and summaries from invited speakers are available below, while abstracts are published in the Pharmacy Education Journal (PEJ) here.
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Application of virtual clinical studies using physiologically-based pharmacokinetic model to analyses of the association of side effects of CPT-11 with genetic polymorphism of enzymes and transporters
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-069-Tuesday
- By: TOSHIMOTO, Kota (Yokohama, Japan)
- Co-author(s): Kota Toshimoto: Sugiyama Laboratory, RIKEN Innovation Center, RIKEN, Yokohama, Japan
Atsuko Tomaru: Sugiyama Laboratory, RIKEN Innovation Center, RIKEN, Yokohama, Japan
Masakiyo Hosokawa: Faculty of Pharmaceutical Sciences, Chiba Institute of Science, Choshi, Japan
Yuichi Sugiyama: Sugiyama Laboratory, RIKEN Innovation Center, RIKEN, Yokohama, Japan - Abstract:
Backgrounds
Many controversial associations between various genetic polymorphisms and side effects of CPT-11 (neutropenia and diarrhea) have been reported.Aims
The purpose of this study is to develop a physiologically-based pharmacokinetic (PBPK) model to gain insight into the factors associated with side effects of CPT-11 using a virtual clinical .. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.
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Last update 23 September 2026