Pyxinol ameliorates cisplatin-induced nephrotoxicity without compromising its anti-tumor activity

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-062-Tuesday
• By: WANG, Hongbo (Yantai, China)
• Co-author(s): Jinbo Ma: Key lab of Molecular Pharmacology and drug evaluation , Yantai University, Yantai, China
  Yanting Yang: Key lab of Molecular Pharmacology and drug evaluation, Yantai University, Yantai, China
  Hongbo Wang: Key Lab of Molecular Pharmacology and Drug Evaluation, Yantai University, Yantai, China
  Fenghua Fu: Key lab of Molecular Pharmacology and drug evaluation, Yantai University, Yantai, China
  
• Abstract:

  Backgrounds

  Cisplatin is a chemotherapeutic agent against solid tumors, however, the cisplatin time- and dose-dependent nephrotoxicity is the main adverse effect of cisplatin. 

  Aims

  In this study, we investigated whether the pyxinol (DQ) had protective effects against cisplatin-induced nephrotoxicity. 

  Methods

  To clarify it, one in vivo model of
  ..

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