Changes in the pharmacokinetics of fluvastatin, atorvastatin, and simvastatin but not of rosuvastatin and pravastatin in collagen-induced arthritis rats

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-084-Monday
• By: LIN, Chun-Jung (National Taiwan University, School of Pharmacy, Taipei, China Taiwan)
• Co-author(s): Chun-Han Lin: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
  Ke-Wei Hsu: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
  Chia-Hao Chen: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
  Yow-Shieng Uang: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
  Chun-Jung Lin: School of Pharmacy, National Taiwan University, Taipei, Taiwan, Province of China
  
• Abstract:

  Backgrounds

  The elevated systemic levels of cytokines in rheumatoid arthritis (RA) can change the expression of metabolic enzymes and transporters. Statins are lipid-lowering agents frequently used in RA patients with concurrent cardiovascular diseases. 

  Aims

  The objective of the present study was to investigate the impacts of RA on the
  ..

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