Discovery and identification of Hsp90-Cdc37 PPI modulators through multiple drug discovery strategies

• In: Poster Presentation
• At: Stockholm (Sweden) (2017)
• Type: Poster
• Poster code: P-A-048-Monday
• By: WANG, Lei (China Pharmaceutical University, Department of Medicinal Chemistry, NANJING, China)
• Co-author(s): Lei Wang: Department of Medicinal Chemistry, China Pharmaceutical University, NANJING, China
  Ruoning Wang: Department of Medicinal Chemistry, China Pharmaceutical University, NANJING, China
  Qidong You: Department of Medicinal Chemistry, China Pharmaceutical University, NANJING, China
  
• Abstract:

  Backgrounds

  Targeting Hsp90-Cdc37 PPI is becoming an alternative approach for future anti-cancer drug development. However, up to now, there is no small molecule reported which make this target an interesting and challenging one for drug discovery.

  Aims

  Finding Hsp90-Cdc37 PPI modulators with high affinity and selectivity as an alternative strategy
  ..

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