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Construction and application of biotin–poloxamer conjugate micelles for chemotherapeutics
- In: Posters: Formulation Design and Pharmaceutical Technology
- At: Bangkok (Thailand) (2014)
- Type: Poster
- Poster code: POS-FDP033
- By: LIN, Guang-Yong (The Second Affiliated Hospital of Wenzhou Medical College, department of Pharmacy, Wen zhou, China)
- Abstract:
ABSTRACT: OBJECTIVE Biotin was conjugated on poloxamer to prepare biotin-poloxamer (BP) conjugate micelles for chemother-apeutics. METHODS Epirubicin (EPI) was encapsulated in BP micelles. The EPI-loaded BP micelles were characterized in terms of size, -potential, morphology, drug loading, drug encapsulation and drug release. Marrow leuke-mic..
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Last update 2 July 2026