Construction and application of biotin–poloxamer conjugate micelles for chemotherapeutics

• In: Posters: Formulation Design and Pharmaceutical Technology
• At: Bangkok (Thailand) (2014)
• Type: Poster
• Poster code: POS-FDP033
• By: LIN, Guang-Yong (The Second Affiliated Hospital of Wenzhou Medical College, department of Pharmacy, Wen zhou, China)
• Abstract:

  ABSTRACT: OBJECTIVE Biotin was conjugated on poloxamer to prepare biotin-poloxamer (BP) conjugate micelles for chemother-apeutics. METHODS Epirubicin (EPI) was encapsulated in BP micelles. The EPI-loaded BP micelles were characterized in terms of size, -potential, morphology, drug loading, drug encapsulation and drug release. Marrow leuke-mic..

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