The in vitro profile assessment of fluticasone propionate and cyclodextrins binary systems

• In: Posters: Formulation Design and Pharmaceutical Technology
• At: Bangkok (Thailand) (2014)
• Type: Poster
• Poster code: POS-FDP017
• By: Sá COUTO, André (Faculty of Pharmacy University of Lisbon, Pharmaceutical Technology, Lisbon, Portugal)
• Co-author(s): Monod, Stephanie (Faculty of Pharmacy University of Lisbon, Lisbon, Portugal)
  Cabral-Marques, Helena (Faculty of Pharmacy University of Lisbon, Lisbon, Portugal)
  
• Abstract:

  I.Background information:To overcome the limitation of corticosteroids formulations (namely high lipophilicity), its association with cyclodextrins (CyDs) has been used to improve the water solubility and to reduce the dose required to get a local effect at lungs, thus reducing their side effects.
  CyDs are non-toxic excipients with a lipophylic..

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