Preparation and characterization of binary amorphous precipitates of ritonavir and quercetin

• In: Posters: Formulation Design and Pharmaceutical Technology
• At: Bangkok (Thailand) (2014)
• Type: Poster
• Poster code: POS-FDP005
• By: DENGALE, Swapnil (Manipal college of pharmaceutical sciences, Department of Pharmaceutical Quality Assurance, Manipal, India)
• Co-author(s): Ranjan, Om Prakash (Manipal college of pharmaceutical sciences, Manipal, India)
  Bhat, Krishnamurthy (Manipal college of pharmaceutical sciences, Manipal, India)
  
• Abstract:

  I Background: Ritonavir is the protease inhibitor with very low bioavailability due to its limited aqueous solubility (BCS Class-II member). Several attempts have been made to stabilize amorphous form of Ritonavir. We attempted to stabilize Ritonavir in amorphous form by using binary amorphous technique with proven pg-p substrate and inhibitor..

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