Low dose drug and lubricant quantification in powder blends by near infrared spectroscopy

• In: J8 - Competition - Short Oral Communications of the FIP Industrial Pharmacy Section on Tuesday, 6 September 2011, 14:15-16:45
• At: Hyderabad (India) (2011)
• Type: Presentations + Posters
• By: MARTINEZ, Lizbeth (University of Basel, Basel, Switzerland)
• Co-author(s): Liesum, Lorenz (Novartis Pharma AG, Basel, Switzerland)
  Betz, Gabriele (University of Basel, Basel, Switzerland)
  
• Abstract:

  Blending is a fundamental but critical process in the manufacture of solid dosage forms, especially for the formulations containing low dose drugs. Near infrared (NIR) spectroscopy has shown a great potential in real-time monitoring of powder blending processes.
  The aim of this study was to predict the low load components (drug and lubricant) in a

  ..

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