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Use of NIR and MRI in dissolution testing

  • In: C2 - Why is Dissolution Testing still needed? on Monday, 30 August 2010, 9:00-12:00
  • At: Lisbon (Portugal) (2010)
  • Type: Presentation
  • By: TERADA, Katsuhide (Toho University, Funabashi, Japan)
  • Co-author(s): Ito, Masatomo (Daiichi Sankyo Co. Ltd, Hiratsuka, Japan)
  • Abstract:

    A comparison between dissolution profiles by using a dissolution apparatus and the NIR spectrum was performed for controlled release bi-layer tablets containing acetaminophen. Taking into consideration of the variation of tabletting process, tablets were prepared with fifteen different conditions. The variable parameters that we have considered

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