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Biorelevant dissolution testing
- In: C2 - Why is Dissolution Testing still needed? on Monday, 30 August 2010, 9:00-12:00
- At: Lisbon (Portugal) (2010)
- Type: Presentation
- By: DRESSMAN, Jennifer (Goethe University, Frankfurt am Main, Germany)
- Abstract:
In the late 1990s, biorelevant dissolution testing emerged as a new tool for predicting in vivo behaviour of oral dosage forms. Test conditions were established which simulate the main features of upper gastrointestinal (GI) physiology under either fasted or fed state conditions. By testing the dissolution profile of the API under these
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