Genomewide approaches to discovering drug safety biomarkers

• In: Symposium E1: Clinical Implementation of Precision Medicine: From genomewide discovery to practice  on Monday, 22 May 2017, 15:00-15:10
• At: Stockholm (Sweden) (2017)
• Type: Presentation
• By: PIRMOHAMED, Munir (University Of Liverpool, Molecular And Clinical Pharmacology, Liverpool, United Kingdom)
• Co-author(s): Professor Sir Munir HUSSEIN PIRMOHAMED: Molecular And Clinical Pharmacology, University Of Liverpool, Liverpool, United Kingdom
  
• Abstract:

  Adverse drug reactions (ADRs) are a major clinical problem accounting for a great deal of morbidity, mortality and are a drain on healthcare resources.  ADRs can generally be divided into on-target and off target reactions.  Both types of ADRs have a genetic predisposition, but the quantitative contribution of genetic vs. non-genetic factors

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