Advancing combination drug development through quantitative medicine

• In: Symposium T4: Infectious Diseases: the battle we will win on Wednesday, 24 May 2017, 10:40-11:15
• At: Stockholm (Sweden) (2017)
• Type: Presentation
• By: ROMERO, Klaus (Critical Path Institute, Clinical Pharmacology and Quantitative Medicine, Tucson, United States)
• Co-author(s): Klaus Romero: Clinical Pharmacology and Quantitative Medicine, Critical Path Institute, Tucson, United States
  Debra Hanna: Critical Path to TB Drug Regimens (CPTR) Initiative, Critical Path Institute, Tucson, United States
  
• Abstract:

  The development of novel tuberculosis (TB) multi-drug regimens that are more efficacious and of shorter duration requires a robust drug development pipeline. Advances in quantitative modeling and simulation can be used to maximize the utility of patient-level data from prior and contemporary clinical trials, thus optimizing study design for

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