Recent progress in formulation approaches for oral absorption of biopharmaceuticals

• In: Symposium B4: Oral absorption of biopharmaceuticals revisited on Wednesday, 24 May 2017, 09:45-10:20
• At: Stockholm (Sweden) (2017)
• Type: Presentation
• By: BRAYDEN, David (University College Dublin, Conway Institute, Dublin, Ireland)
• Co-author(s): David Brayden: Conway Institute, University College Dublin, Dublin, Ireland
  
• Abstract:

  Oral delivery of macromolecules remains a great challenge as it requires stability in the GI tract, delivery to the correct intestinal region, adequate epithelial permeability, and avoidance of liver first pass metabolism - all with a process that can be scaled for manufacturing.  For peptides, some of the problems may be addressed by lower

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