intracellular environment-responsive lipid like material as a multi-nanoDDS platform

• In: Short Communications B2 on Monday, 22 May 2017, 13:30-15:00
• At: Stockholm (Sweden) (2017)
• Type: Presentation
• By: AKITA, Hidetaka (Chiba, Japan)
• Co-author(s): Hidetaka Akita: Graduate School of Pharmaceutical Sciences, Chiba Universitry, Chiba, Japan
  
• Abstract:

  Backgrounds

  While the gene therapy approach has faced technical and/or regulatory impediments, a large number of clinical trials are still ongoing worldwide. Gene expression efficacy is rate-limited by the multiple processes (i.e. cellular uptake, endosomal escape, cytoplasmic transport and nuclear delivery). Adequate design to overcome these

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