The role of TLR4 in the gut-brain axis in Parkinson’s disease: a translational study from man to mice.

• In: Short Communications A3 on Tuesday, 23 May 2017, 11:15-12:30
• At: Stockholm (Sweden) (2017)
• Type: Presentation
• By: PEREZ PARDO, Paula (Utrecht University, Pharmacology, Utrecht, Netherlands)
• Co-author(s): Paula Perez Pardo: Pharmacology, Utrecht University, Utrecht, Netherlands
  Hemraj B Dodiya: Medicine, Rush University Medical center, Chicago, United States
  Christopher B Forsyth: Medicine, Rush University Medical center, Chicago, United States
  Johan Garssen: Pharmacology, Utrecht University, Utrecht, Netherlands
  Ali Keshavarzian: Medicine, Rush University Medical center, Chicago, United States
  Aletta D Kraneveld: Pharmacology, Utrecht University, Utrecht, Netherlands
  
• Abstract:

  Backgrounds

  Recent evidence suggesting an important role of gut dysfunction in brain disorders has opened up new directions to explore the possible role of the gut-brain axis in neurodegenerative disorders. 

  Aims

  Given the prominence of colonic dysfunction in Parkinson’s disease patients (PD), we propose that intestinal dysfunction could

  ..

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