Drying and tableting of low water-soluble nanocrystals to improve oral bioavailability
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-C-007-Monday
- By: BRAIG, Veronika (Erlangen, Germany)
- Co-author(s): Veronika Braig: Division of Pharmaceutics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
Christoph Konnerth: Institute of Particle Technology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
Wolfgang Peukert: Institute of Particle Technology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany
Geoffrey Lee: Division of Pharmaceutics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany - Abstract:
Backgrounds
The production of nanocrystals is a strategy to improve the low aqueous solubility of drugs. Following, specific surface and dissolution rate are increased and oral bioavailability is improved. Before being packed into a solid dosage form, nanosuspensions have to be embedded into a dry powder due to stability problems and to increase
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Last update 28 September 2023