High intracellular cholesterol level reduces the sensitivity to EGFR-TKI therapy may via ATP-binding cassette transporters in non-small cell lung cancer harboring EGFR mutations
- In: Poster Presentation
- At: Stockholm (Sweden) (2017)
- Type: Poster
- Poster code: P-A-007-Tuesday
- By: CHEN, Qiufang (China Pharmaceutical University, Nanjing, China)
- Co-author(s): Qiufang Chen: China Pharmaceutical University, Nanjing, China
Chen Qiao: China Pharmaceutical University, Nanjing, China
Wenjuan Ye: China Pharmaceutical University, Nanjing, China
Xiaomei Wu: China Pharmaceutical University, Nanjing, China
Xuansheng Ding: China Pharmaceutical University, Nanjing, China
Liyun Miao: The affiliated Drum Tower Hospital of Nanjing University Medical College, Nanjing, China - Abstract:
Backgrounds
Cancer cells need excess cholesterol to maintain a high level of proliferation is well accepted, however whether intracellular cholesterol level associates with epidermal growth factor receptor-tyrosine kinase inhibitors resistance in non-small cell lung cancer harboring EGFR mutations has not been elucidated.Aims
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Last update 28 September 2023