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Rapid quantitative estimation of siponimod in rat plasma by liquid chromatography- tandam mass spectroscopy and its application to pharmacokinetic studies

  • At: Seville (Spain) (2022)
  • Type: Poster
  • Poster code: NMS-032
  • By: SRILAKSHMI, DARBHAMULLA (Vikas Institute Of Pharmacutical Sciences, India)
  • Co-author(s): Mrs DARBHAMULLA SRILAKSHMI (Vikas Institute Of Pharmacutical Sciences, Rajahmundry, India)
    Dr P Venkateswara Rao, Pharmaceutical Analysis (Vikas college of pharmacy, Vissanapeta, India)
  • Abstract:

    The creation of reliable bioanalytical LC-MS (liquid chromatography-mass spectroscopy) method(s) is critical during the drug discovery, development, and marketing approval processes. Siponimod is a sphingosine – 1 – phosphate (S1P) receptor modulator. Siponimod binds to both S1P receptors, S1P1 and S1P5 with a high affinity. This binding..

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Last update 4 October 2019

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