Remedsevir loaded nanoparticles as potential treatment for COVID-19

• At: Seville (Spain) (2022)
• Type: Poster
• Poster code: NMS-022
• By: MASSADEH, Salam (King Abdullah International Medical Research Center, Saudi Arabia)
• Co-author(s): Dr Salam Massadeh, Research Scientist (King Abdullah International Medical Research Center, Riyadh, Saudi Arabia / King Saud University for Health Sciences, Riyadh, Saudi Arabia / Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia / KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia / Saudi Human Genome Project, King Abdulaziz City for Science and Technology,, Riyadh, Saudi Arabia)
  Dr Manal Alaamery (King Abdullah International Medical Research Center, Riyadh, Saudi Arabia / King Saud University for Health Sciences, Riyadh, Saudi Arabia / Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia / KACST-BWH Centre of Excellence for Biomedicine, Joint Centers of Excellence Program, King Abdulaziz City for Science and Technology (KACST), Riyadh, Saudi Arabia / Saudi Human Genome Project, King Abdulaziz City for Science and Technology,, Riyadh, Saudi Arabia)
  
• Abstract:

  Remdesivir (GS-5734) is a broad-spectrum antiviral prodrug with activity against RNA viruses from several families. It specifically targets viral RNA-dependent RNA polymerase (RdRp) and demonstrates no activities against human RNA pol II or mitochondrial RNA polymerase. Herein ,We attempted to load this drug into Tri-block Poly (lactide) poly..

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