Design, identification, optimisation and validation of selective casein kinase II(CK2) modulator

• At: Seville (Spain) (2022)
• Type: Poster
• Poster code: CBS-010
• By: SHOEMAKE, Claire ()
• Co-author(s): Ms Oksana Friggieri, Pharmacy
  Dr Claire Shoemake, Senior Lecturer
  
• Abstract:

  The CK2 receptor has been acknowledged as a key contributor to carcinogenesis and has been identified as a druggable target in oncology because its inhibition slows down cellular metabolism. GO289 has been identified as a promising molecule for the mitigation of phosphorylation of circadian proteins and proliferation of malignant cells through CK2 ..

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