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Microglial NMDA receptors and mitochondria- derived superoxide mediate aβ1-42 oligomer-induced neurotoxicity in primary rat brain cultures

  • At: Seville (Spain) (2022)
  • Type: Poster
  • Poster code: NMS-023
  • By: MORKUNIENE, Ramune (Institute of Neurosciences, Lithianian University of Health Sciences, Lithuania)
  • Co-author(s): Prof Ramune Morkuniene, Institute of Neurosciences, Faculty of Pharmacy (Institute of Neurosciences, Lithianian University of Health Sciences, Kaunas, Lithuania / Faculty of Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania)
    Dr Aiste Jekabsone, Faculty of Pharmacy (Faculty of Pharmacy, Lithuanian University of Health Sciences, Kaunas, Lithuania)
    Dr Silvija Jankeviciute, Institute of Neurosciences (Institute of Neurosciences, Lithianian University of Health Sciences, Kaunas, Lithuania)
    Dr Katryna Pampuscenko, Institute of Neurosciences (Institute of Neurosciences, Lithianian University of Health Sciences, Kaunas, Lithuania)
    Prof Vilmante Borutaite, Institute of Neurosciences (Institute of Neurosciences, Lithianian University of Health Sciences, Kaunas, Lithuania)
  • Abstract:

    Aging is the main risk factor for most neurodegenerative diseases, including Alzheimer disease (AD). More than 55 million people suffer from dementia and there is currently no effective treatment available to cure aging-related neurodegenerative diseases. The pathology of AD involves abnormal accumulation of amyloid beta (Aβ) and the link between ..

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Last update 28 September 2023

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