Release profiles and in vivo bioavailability in beagle dogs of Rebamipide nanosuspension-loaded bilayer tablet

• At: Seville (Spain) (2022)
• Type: Poster
• Poster code: DDD-017
• By: LEE, Beom-Jin (Ajou University, South Korea)
• Co-author(s): Prof Beom-Jin Lee (Ajou University, Suwon, South Korea)
  Mr Gang Jin (Ajou University, Suwon, South Korea / Jilin Institute of Chemical Technology, Jilin, China)
  Mr Hai Ngo (Ajou University, Suwon, South Korea)
  
• Abstract:

  Novel bilayer matrix tablet loaded with immediate release (IR) nanosuspension and sustained release (SR) of rebamipide (RBM) was developed to be effectively delivered in a controlled manner for one day. Salt-caged RBM nanosuspensions (NSPs) was designed to overcome the pH-dependent poor water solubility of RBM in low pH condition using an..

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