• Join
  • Login
  • Contact

Search abstracts

Intestinal absorption of the prodrug Olmesartan Medoxomil is enhanced by oatp2b1-mediated uptake

  • At: Seville (Spain) (2022)
  • Type: Poster
  • Poster code: DDD-010
  • By: FUKAZAWA, Naomi (Keio University, Japan)
  • Co-author(s): Ms Naomi Fukazawa, Faculty of Pharmacy (Keio University, Minato-ku, Japan)
    Dr Saki Noguchi (Keio University, Minato-ku, Japan)
    Dr Tomohiro Nishimura (Keio University, Minato-ku, Japan)
    Professor Masatoshi Tomi (Keio University, Minato-ku, Japan)
  • Abstract:

    Background: Ester-prodrugs generally have a neutral charge at physiological pH and are orally absorbed via passive diffusion in the small intestine. Olmesartan medoxomil (OL-MX), an ester-prodrug of olmesartan (OL), is an oral approved-drug of angiotensin II receptor blockers (ARBs) and presents in the form of anions at intestinal pH. Organic..

  • The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 4 October 2019

FIP Congresses